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Increasing the Immune Defense of Skin

Posted by Nancy Ray on

The skin barrier, composed of lipids and essentially dead cells (corneocytes) in the upper layer of the epidermis (stratum corneum), plays a major role in protecting the body from numerous insults including microbial invasion. However, when compromised, the skin’s immune system is activated to defend the body from further damage and infection. Skin immunity involves the skin microbiome (collective set of microorganisms on the skin), antimicrobial peptides (short chains of amino acids) and a variety of signaling molecules that activate or suppress certain immune cells such as dendritic cells (including Langerhan’s cells), macrophages, neutrophils and mast cells.  When damage and/or...

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Defending Against Microbial Infections and Biofilms

Posted by Nancy Ray on

Skin provides a fairly inhospitable environment for most microbes due to its amazing ability to remain cool, dry and slightly acidic.  In addition to producing sweat, the skin frequently sheds cells and secretes oils and defensive peptides to protect against invading microbes.  However, skin isn’t completely hostile to microbes because it also welcomes a rich and complex flora of interacting microbes that live in harmony with the skin and actually protect it from dangerous pathogens. Viniferamine® skin and wound care products were designed to preserve the balance of the skin’s normal chemistry and flora and enhance protection against invading microbes...

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