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Increasing the Immune Defense of Skin

Posted by Nancy Ray on

The skin barrier, composed of lipids and essentially dead cells (corneocytes) in the upper layer of the epidermis (stratum corneum), plays a major role in protecting the body from numerous insults including microbial invasion. However, when compromised, the skin’s immune system is activated to defend the body from further damage and infection. Skin immunity involves the skin microbiome (collective set of microorganisms on the skin), antimicrobial peptides (short chains of amino acids) and a variety of signaling molecules that activate or suppress certain immune cells such as dendritic cells (including Langerhan’s cells), macrophages, neutrophils and mast cells.  When damage and/or...

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Handwashing Awareness

Posted by Nancy Ray on

Handwashing is important because it helps eliminate germs that can cause disease.  In fact, good hand hygiene has been linked to a decrease in infectious disease incidence.  Unfortunately, it’s too easy to forget the vital importance of handwashing due to the fact that antibiotics and vaccines have contributed so significantly to declining infectious disease-associated mortality over the past 100 years.   However, this trend should not be taken for granted, since mortality in the U.S. from infectious diseases actually rose between 1980 and 1992 due to an unexpected increase in emerging infectious diseases such as antibiotic resistant tuberculosis. Over the last...

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Defending Against Microbial Infections and Biofilms

Posted by Nancy Ray on

Skin provides a fairly inhospitable environment for most microbes due to its amazing ability to remain cool, dry and slightly acidic.  In addition to producing sweat, the skin frequently sheds cells and secretes oils and defensive peptides to protect against invading microbes.  However, skin isn’t completely hostile to microbes because it also welcomes a rich and complex flora of interacting microbes that live in harmony with the skin and actually protect it from dangerous pathogens. Viniferamine® skin and wound care products were designed to preserve the balance of the skin’s normal chemistry and flora and enhance protection against invading microbes...

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