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Providing Penetrating Nutrition to Promote Skin Health

Posted by Nancy Ray on

The small molecule technology found in Viniferamine® products delivers penetrating nutrition to epidermal cells to promote skin cell repair and skin renewal. Viniferamine® skin and wound care products provide nutrition to the epidermis to strengthen the skin barrier and enhance overall skin health. Small molecules under the molecular weight of 500 daltons are able to pass into the stratum corneum (uppermost layer of the epidermis), which is known as the “500-dalton rule.” The small molecules contained in Viniferamine® skin and wound care products that include antioxidants, amino acids and vitamins enter the skin, reduce excessive transepidermal water loss, and scavenge-free...

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Increasing the Immune Defense of Skin

Posted by Nancy Ray on

The skin barrier, composed of lipids and essentially dead cells (corneocytes) in the upper layer of the epidermis (stratum corneum), plays a major role in protecting the body from numerous insults including microbial invasion. However, when compromised, the skin’s immune system is activated to defend the body from further damage and infection. Skin immunity involves the skin microbiome (collective set of microorganisms on the skin), antimicrobial peptides (short chains of amino acids) and a variety of signaling molecules that activate or suppress certain immune cells such as dendritic cells (including Langerhan’s cells), macrophages, neutrophils and mast cells.  When damage and/or...

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Decreasing Obesity-Related Skin Issues

Posted by Nancy Ray on

According to recent estimates, at least 35% of Americans are classified as obese, and this trend towards obesity is only increasing. Obesity is defined as a state of excess adiposity (accumulation of lipids) due to prolonged positive energy imbalance. Obesity is also defined as a body mass index (BMI) of 30kg/m or greater. There are multiple causes for obesity including, diet, genetics, inactivity or weight gain related to drugs such as oral corticosteroids, oral contraceptives, or serotonin reuptake inhibitors (antidepressants). Obesity increases the risk involved with more than 30 medical problems including skin issues.  Obesity is associated with oxidative stress...

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Enhancing Diabetic Skin Health

Posted by Nancy Ray on

Diabetes mellitus is a metabolic disorder associated with chronic inflammation that can lead to various health complications including foot ulcers.  The most common form, type 2 diabetes, involves insulin resistance and decreased insulin production.  Increased blood glucose or hyperglycemia is also common in diabetics.  In addition, at least 30% of individuals with diabetes have some form of skin problem.  Skin dryness, itching (pruritus), skin infection, and impaired wound healing are some of the common problems that can be associated with diabetes. Dry skin is due to the fact that individuals with diabetes tend to have reduced skin hydration resulting from...

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Defending Against Microbial Infections and Biofilms

Posted by Nancy Ray on

Skin provides a fairly inhospitable environment for most microbes due to its amazing ability to remain cool, dry and slightly acidic.  In addition to producing sweat, the skin frequently sheds cells and secretes oils and defensive peptides to protect against invading microbes.  However, skin isn’t completely hostile to microbes because it also welcomes a rich and complex flora of interacting microbes that live in harmony with the skin and actually protect it from dangerous pathogens. Viniferamine® skin and wound care products were designed to preserve the balance of the skin’s normal chemistry and flora and enhance protection against invading microbes...

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Vitamin C and Skin Health

Posted by Nancy Ray on

Vitamin C is an essential nutrient for skin as well as the rest of the body.  It’s absolutely necessary for normal skin and bodily functions, cannot be naturally synthesized in humans and must be provided externally. Skin itself has various critical roles in overall health including protection from dehydration and infection, and its appearance is an important reflection on general well-being. The epidermal layer of skin is responsible for most of its barrier function and includes many cells, particularly keratinocytes. In contrast, the lower dermal layer is composed mainly of fibroblasts that secrete the major component of the dermis, collagen...

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Avoiding Skin Irritation that Can Lead to Wounding

Posted by Nancy Ray on

Taking optimal care of skin is vital for overall health and wellbeing. In fact, keeping skin intact and healthy is critical for maintaining homeostasis including proper body temperature and hydration. Skin also provides a barrier to pathogens and chemicals that could cause systemic disease and/or damage. When skin is exposed to irritants, it often becomes inflamed and itchy, and it’s difficult not to scratch.  Unfortunately, scratching can result in wounds. Various factors are important for a well functioning skin barrier including proper skin pH, balanced lipids and healthy microbial flora (microbiome). Factors that can disturb barrier function include stress (including...

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Reducing Dermal Scarring

Posted by Nancy Ray on

Scars are areas of dermal fibrosis that replace normal tissue after injury and during wound healing. There are several types of dermal scars including: 1. Atrophic scars that appear as sunken or pitted areas of skin 2. Hypertrophic scars that are characterized by raised areas of skin 3. Keloid scars characterized by growth outside the original wound area 4. Striae distensae (stretch marks) characterized by linear bands of atrophic-appearing skin. Wound healing involves 4 critical phases that overlap: the coagulation phase, the inflammatory phase, the migration-proliferation phase (development of granulation tissue), and the remodeling-regeneration phase that includes maturation, scar formation...

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Reducing Air Pollution Damage to Skin

Posted by Nancy Ray on

Air pollution is becoming an increasing health problem worldwide. It’s an environmental threat to which millions of people are exposed, and is currently the world’s largest single environmental health risk.  It’s well known that air pollution is bad for lungs, but scientist are just beginning to discover how damaging air pollution is to the skin.  Viniferamine® skin and wound care products were designed to protect skin from irritants, and help restore skin cells naturally back to health.  Not only is outdoor air pollution a risk to skin health, but indoor air pollution can also be harmful.  Indoor risks include exposure...

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Strengthening Fragile Skin to Reduce Skin Tears

Posted by Nancy Ray on

Fragile, thinning skin and skin tears are common issues among older individuals.  A skin tear is a wound caused by shear, friction, and/or blunt force resulting in the separation of skin layers.  Skin tears can be either partial thickness (separation of the epidermis from the dermis) or full thickness (separation of both the epidermis and the dermis from the subcutaneous tissue).  Loss of cohesion between the skin layers allows the skin to move independently, resulting in tears with even minor forces including tape removal from skin. Skin tears may be considered by some as minor injuries, but in fact, they...

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