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The Importance of Skin Lipids

Posted by Nancy Ray on

The Importance of Skin Lipids The stratum corneum or uppermost layer of the epidermis has been described of as consisting of bricks and mortar.  Long thought of as an inactive layer of dead skin cells, in contrast, the stratum corneum is highly dynamic.  The bricks are the corneocytes or differentiated keratinocytes that are tightly connected by links called corneodesmosomes and the mortar is the extracellular space composed of highly ordered lamellar lipids that form membranes.  The lipids within the extracellular spaces help provide a barrier to moisture and electrolyte loss from the skin that is absolutely required for survival.  These...

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Decreasing Sun Sensitivity Inflammation

Posted by Nancy Ray on

Exposure to the sun can cause UV-induced damage to DNA in skin cells resulting in inflammation known as sunburn. Skin contains molecules that absorb UV radiation such as DNA and other chromophores. The absorbed energy is then re-emitted as harmless, longer wavelength radiation or cell-damaging thermochemical reactions involving free-radical reactive oxygen species (ROS) generation and oxidative stress. Viniferamine® skincare products, including Renewal Moisturizer, contain ingredients that counteract oxidative stress such as oleuropein, resveratrol, EGCG, melatonin, and L-glutathione. Oxidative stress typically results in inflammation; various ingredients found in Viniferamine® skincare products decrease inflammation including the beneficial polyphenols oleuropein, resveratrol, and epigallocatechin-3-gallate...

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Helping Decrease Rashes

Posted by Nancy Ray on

Helping Decrease Rashes There are many different kinds of rashes that have various causes. Some rashes are associated with fever and/or serious illnesses and should be brought to the attention of a healthcare professional immediately. Here we will mainly focus on more common rashes not typically associated with fever. Rashes generally cause the skin to change color and can be accompanied by inflammation, itching (pruritus), blisters, swelling and pain. Many rashes are nonspecific. They can last from 5 to 20 days and can be associated with problematic issues such as irritations, sunburn, allergies, eczema, infections (including yeast infections), cancer, autoimmune...

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Reducing Xerosis (Abnormally Dry Skin)

Posted by Nancy Ray on

Xerosis or abnormally dry skin is a common skin problem especially among older individuals. With normal (or intrinsic) skin aging, as opposed to skin aged by the sun, skin becomes thinner, has a decreased amount of blood flow and lipids, and collagen in the skin becomes fragmented resulting in drier, more colorless skin with fine wrinkles. In contrast, photoaging (or extrinsic aging) caused by UV radiation is characterized by the accumulation of abnormal elastin in the skin and the disintegration of collagen resulting in deep wrinkles, hyperpigmentation (age or liver spots) and a leathery appearance of the skin. Xerosis is...

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Protecting the Skin Microbiome

Posted by Nancy Ray on

It’s estimated that approximately 1000 different species of bacteria are included in the 1 billion microorganisms that live on each square centimeter of our skin. It is now becoming quite clear that the skin microbiome (collective set of microorganisms and their genetic material) modulates skin diseases, influences metabolic processes and is important for skin immunity. The diversity of the skin microbiome is influenced by various factors including transient microbes, genetic predispositions, location and environmental characteristics. In 2007, the National Institute of Health provided funding for a Microbiome Project Consortium to characterize the human microbial communities present at specific body locations...

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Polyphenols, Endothelial Function and Wound Healing

Posted by Nancy Ray on

The normal wound repair process is divided into four overlapping phases of coagulation, inflammation, migration-proliferation, and remodeling. This complex process involves the interplay of different cell types including keratinocytes, fibrobrasts and endothelial cells. Endothelial dysfunction and oxidative stress that can occur for example with type 2 diabetes or as a result of radiation exposure (during cancer radiation therapy) frequently contributes to impaired wound healing and skin repair. Oxidative stress typically leads to inflammation and results from the inability of cells to eliminate free radicals known as reactive oxygen species (ROS) using the natural defense system that includes enzymes such as...

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Eliminating the Risk of Parabens in Skin and Wound Care

Posted by Nancy Ray on

Parabens were first used in the mid1920s for their antimicrobial properties. By the early 2000s, parabens were found in over 90% of cosmetic products. Parabens are a group of alkyl esters of p-hydroxybenzoic acid (PHBA) including methylparaben, ethylparaben, propylparaben, butylparaben, isobutylparaben, isopropylparaben and benzylparaben. Paraben compounds are either used alone or as a mixture in products to increase their efficacy. In fact, currently, parabens are widely used as preservatives in many products including cosmetics, skincare, toothpaste, underarm deoderants, pharmaceuticals and food packaging products, in part due to their low cost, as well as lack of color and odor. Viniferamine® skin...

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Relief from Itching

Posted by Nancy Ray on
Itch or pruritus has been defined as an unpleasant sensation that elicits the desire or reflex to scratch. Itch is the most common symptom in dermatology. It is also the most common skin complaint in people over the age of 65 years and it can have a major impact on an individual’s quality of life.

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Fight Cancer with Sleep

Posted by Kyle Hilsabeck on

Most people would agree that nothing really beats a great night of restful sleep. Most cells in your body would also agree that they appreciate a good night’s rest. However, there are certain types of cells that cannot stand it when you get a full night of great sleep – and those are cancer cells.  We know that sleep is important for feeling rested and energetic during the day, improving mood, immunity, work performance, heart health, cognition – more things than can possibly be imagined. But would you believe that the quality and amount of sleep you get could actually...

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The Extraordinary Benefits of Aloe Vera in Skin Health and Wound Healing

Posted by Nancy Ray on

For centuries, aloe vera has been prized for its medicinal properties that include the enhancement of skin health and healing. In fact, aloe plants have been used for over 2000 years in the treatment of skin diseases; ancient Egyptians called it “the plant of immortality” and early Greek physicians considered it a universal panacea. Aloe vera contains at least 75 components, many of which that are known to promote skin health and wound healing such as beneficial vitamins, minerals and amino acids. Vitamins that come from aloe vera include important B vitamins, vitamin C and vitamin E. Aloe vera also...

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